Prescription vs Over-the-Counter Medicines in the EU: What You Can (and Can’t) Buy Online

One of the biggest reasons people abandon an online pharmacy checkout in Europe is simple confusion.

Do I need a prescription for this?
Why was my order blocked?
Can I buy this online in one country but not another?

These are fair questions, and the EU doesn’t always make the answers obvious. But the rules themselves are clearer than most people think.

Here’s how prescription and over-the-counter medicines work in the EU, what you’re legally allowed to buy online, and where country-specific differences come into play.

The two categories that matter in the EU

Across the EU, medicines are split into two legal categories:

• Prescription-Only Medicines (POM)
• Over-the-Counter Medicines (OTC)

This classification exists in every EU member state. The difference isn’t marketing, it’s law.

Over-the-counter medicines: What you can buy online

OTC medicines are those considered safe for use without direct medical supervision, when taken as directed.

In most EU countries, OTC medicines can legally be sold online by licensed pharmacies.

Typical examples include:

• Pain relief (paracetamol, ibuprofen at standard doses)
• Cold and flu treatments
• Allergy medicines
• Heartburn and indigestion remedies
• Some skin treatments and antifungals
• Certain vitamin and mineral supplements

What to expect when buying OTC online

Even though these don’t require a prescription, legitimate EU pharmacies may still:

• Limit quantities
• Ask basic health questions
• Provide mandatory safety information

This isn’t overreach. It’s part of EU patient-safety standards.

If an online pharmacy sells OTC medication with zero information or safeguards, that’s not convenience, it’s a red flag.

Prescription medicines: What you can’t buy without a prescription

Prescription-only medicines are tightly regulated across the EU. These include:

• Antibiotics
• Hormonal treatments
• Blood pressure medication
• Strong painkillers
• Medicines for chronic or complex conditions

The rule is simple

If a medicine requires a prescription in the EU:

• You cannot legally buy it online without one
• No exceptions
• No “online doctor approval” shortcuts

Any website offering prescription medicine without verifying a valid prescription is operating illegally.

That’s not opinion. That’s EU law.

Can you buy prescription medicine online with a prescription?

Yes, and this is where many people get confused.

Licensed EU pharmacies are allowed to sell prescription medicines online, provided:

• A valid prescription is supplied
• The pharmacy is authorised in its home country
• Cross-border rules are followed

This means online pharmacies aren’t breaking the rules by selling prescription medication. They’re only breaking the rules if they skip the prescription check.

EU-wide rules vs country-specific differences

Here’s the part most guides gloss over.

While EU law sets the framework, individual countries still decide how certain medicines are classified.

That means:

• A medicine may be OTC in one country and prescription-only in another
• Dosage limits can differ
• Pack sizes may vary

For example:

• Some allergy medicines are OTC in Germany but prescription-only elsewhere
• Certain painkillers are sold online in limited strengths depending on the country

This is why legitimate online pharmacies sometimes restrict products based on delivery location. It’s compliance, not inconsistency.